The levels of serum anti-müllerian hormone in women with premature ovarian failure and its clinical significance
- VernacularTitle:卵巢早衰患者血清抗苗勒管激素水平测定及其临床意义
- Author:
Haibo ZHAO
;
Yarong HE
- Publication Type:Journal Article
- Keywords:
Ovarian failure,premature/BL;
Mullerian ducts;
Hormones/BL
- From:
Journal of Chinese Physician
2009;11(7):919-920
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of serum anti-mttllerian hormone (AMH) level in women with premature ovarian fail-ure (POF) and its clinical significance. Methods Fasting serum levels of AMH in 25 POF patients were measured with enzyme-linked im-mtmosorbent assay (ELISA). Twenty healthy women matched for age and body mass index (BMI) were chosen as controls. Results The serum AMH level in POF group was (1.1±0.1) pmol/L, which was significantly lower than that of control group(P < 0.01). The serum AMH levels in 20 patients of POF group were undetectable. The other 5 patients were treated with artificial cycle at first, and then ovulated with hMG/HCG.2 patients had ovulation and 1 patient was pregnant. Conclusion The serum AMH level in POF patients was significantly decreased, and the measure for serum AMH had some significance for POF diagnosis and treatment.
