Evaluation of Chorioretinal Toxicity of Steroid after Intrachoroidal Injection in Rabbit.
- Author:
Hyung Woo KWAK
1
;
Jong Geun SHIN
;
Jae Myung KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Kyunghee University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Chorioretinal toxicity;
Intrachoroidal needle insertion;
Methylprednesolone;
Pathology;
Triamcinolone
- MeSH:
Choroid;
Electroretinography;
Microscopy, Electron;
Pathology;
Triamcinolone;
Triamcinolone Acetonide
- From:Journal of the Korean Ophthalmological Society
1995;36(5):787-792
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To determine the ocular toxicity after intrachoroidal steroid injection in the rabbit eye, 0.15ml(40 mg/ml) triamcinolone acetonide, 0.15ml(40 mg/ml) methylprednisol one acetate and 0.15ml balanced salt solution(as controls) were injected into the choroid. The results were shown normal in fundus examination, electroretinography, and electron microscopy throughout the two weeks course of the experiment. From these result, it would appear that intrachoroidal 6 mg steroid injection demonstrated the lack of ocular toxicity.