Clinical observation for long-term domiciliary oxygen therapy on chronic obstructive pulmonary disease
10.3760/cma.j.issn.1673-4904.2009.22.008
- VernacularTitle:慢性阻塞性肺疾病长期家庭氧疗的临床观察
- Author:
Zhanxiang LIU
;
Yanli LI
;
Anmeng WEI
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
Long-term domiciliary oxygen thetapy
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(22):21-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of long-term domiciliary oxygen therapy (LTDOT) on chronic obstructive pulmonary disease(COPD).Methods COPD patients were randomly divided into LTDOT group and control group,LTDOT group received LTDOT on basis of conventional therapy,and control group only received conventional thempy.The lung function,blood gas analysis was detectedand quality of life in paracmasis before and after treatment was evaluted.Results After two years, FEV1[(1.42±0.42)L],PaO2[(80.0±2.6)mm Hg,1 mm Hg=0.133 kPa]in LTDOT group were obviously higher than those in control group[(0.72±0.38)L,(55.0±2.2)mm Hg],there were significant differences between two groups(P<0.01).FVC,PaCO2 in two groups were no significant difference(P>0.05).Quality of life in LTDOT group was better than that in control group,average emergency frequency[(2.3±1.2)times] and hospital day[(16.0±2.4)d]in LTDOT group were obviously decwatsed than those in control group [(5.2±1.3)times,(36.0±2.2)d](P<0.01).Conclusion For the patients with COPD paracmasis, LTDOT can increase FEVI,PaO2,elevate quality of life and decrease average emergency frequency and hospital day.
