Effects of alprostadil and low dose dopamine in treatment of hepatorenal syndrome
10.3760/cma.j.issn.1008-6706.2009.07.008
- VernacularTitle:前列地尔联合小剂量多巴胺治疗肝肾综合征
- Author:
Xiaolin DAI
;
Yunhui ZHONG
;
Xiaoshan HE
;
Zhen HUANG
- Publication Type:Journal Article
- Keywords:
Hepatorenal syndrome;
Alprostadil;
Dopamine
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(7):1166-1167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of alprostadil (Lipo-PGE) combined low-dose dopamine in the treatment of hepatorenal syndrome (HRS). Methods 61 patients with hepatorenal syndrome were randomly di-vided into two groups, treatment group 31 cases, 30 cases of the control group. Treatment group in the control group based on the 20μg soluble in 10% glucose infusion 100 ml in combined treatment with Lipo-PGE a day, one time,and combined with low-dose dopamine 3 μg/(kg·min) intravenous infusion, 1 week course of treatment. Result The treatment group liver function improvement in renal function are superior to the control group (P <0.01), to-ted effective rate was 67.7%. Conclusion The united alprostadil and low-dose dopamine satisfied with liver and kidney syndrome, there is synergy.
