Study on influence of flavonoides from Oroxylum indicum Vent. towards alpha-chymotrypsine in relationship with the process of inflammation
- Author:
Nguyen Xuan Thang
- Publication Type:Journal Article
- Keywords:
Flavonoid, Oroxylum indicum Vent
- MeSH:
Flavonoids;
Inflammation;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
2005;0(8):23-26
- CountryViet Nam
- Language:Vietnamese
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Abstract:
This study demonstrated that in vitro, flavonoids from Oroxylum indicum stimulated the hydrolyzing reaction of alpha-chymotrypsin on casein. The stimulative level was dependent on time exposure and concentration of the flavonoids. In vivo, Oroxylum indicum's flavonoids had anti-inflammatory effects in dextran-induced oedema of mouse paw. When Oroxylum indicum's flavonoids were combined with alpha-chymotrypsin, their anti-inflammatory activity was increased. The successful combination between flavonoids from Oroxylum indicum and alpha - CT contributed to study anti-inflammatory effect of flavonoid and alpha - CT. It may be necessary to further study on traditional and modern anti-inflammatory medication in combination with anti-inflammatory enzyme
