Comparing of dose distribution between intensity-modulated radiotherapy simultaneous integrated boost and conventional radiotherapy for cervical cancer patients

VernacularTitle:宫颈癌调强放疗同步补量与常规照射剂量分布比较
Author: Lihong ZHU ; Bo XU ; Hao WU ; Xing SU ; Shukui HAN
Publication Type:Journal Article
Keywords: Cervical neoplasms; Intensity-modulated radiotherapy simultaneous integrated boost; Conventional radiotherapy; Dose distribution
From: Chinese Journal of Radiological Medicine and Protection 2009;29(4):405-409
CountryChina
Language:Chinese
Abstract: Objective To assess the feasibility of applying intensity-modulated radiotherapy(IMRT)simultaneous integrated boost(SIB)to replace conventional radiotherapy(CR)plus brachytherapy of whole pelvis in locally advanced cervical eaneer(LACC).Methods Five LACC patients based difference position of uterus were chosen and worked out CR and IMRT SIB plans respectively.Dose distributions were compared between IMRT SIB and CR.Results When uterus was in ante-,neutral-,retro-pnsition and deviation respectively,IMRT SIB could provide enough and homogeneous dose distribution for target volume and reduce irradiated volumes and doses for organs at risk(recta,bladder and small intestine)than CR.The doses of the A,B,and fundus of uterus were higher in IMRT SIB than CR.However,in ease of small intestine was close to or encircled the uterus,the targets volume dose would be inadequacy.Conclusions LACC IMRT SIB's dose distribution is better than CR(except excess ante-position)and may help to treat those patients who couldn't be suitable with brachytherapy.