Evaluation of the value of glomerular filtration rate in the severity of coronary artery stenosis in elder people
10.3760/cma.j.issn.0254-9026.2009.08.010
- VernacularTitle:肾小球滤过率对老年冠心病患者冠状动脉病变程度的评估价值
- Author:
Jian LI
;
Chenglei HUANG
;
Rongying ZHU
;
Xuling XU
;
Xinping LUO
;
Yong LI
;
Haiming SHI
- Publication Type:Journal Article
- Keywords:
Renal insufficiency;
Glomerular filtration rate;
Coronary disease
- From:
Chinese Journal of Geriatrics
2009;28(8):645-648
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo assess the relationship between the estimated glomerular filtration rate (eGFR) and the severity of coronary artery stenosis in elder people. MethodsSix hundred and fifty-seven patients who underwent selective coronary artery angiography were divided into 3 groups according to age: group Ⅰ (202 patients aged <60 years), group Ⅱ (181 patients aged from 60 to 69 years) and group Ⅲ (274 patients aged ≥70 years). According to the simplified MDRD equation,impaired renal function and severe renal dysfunction, respectively. Clinical features and the severity of coronary artery stenosis were compared among the 3 groups. ResultsThe level of average eGFR tended to he decreased with the narrowed coronary arteries. The difference of average eGFR between patients with muhivessel versus two-vessel coronary artery disease was of statistical significance in Group Ⅲ(P = 0. 035). After controlling for the effects of smoking, hypertension, dyslipidemia,aging, and diabetes, the Gensini score which reflected the severity of coronary artery stenosis was negatively correlated with the level of eGFR (r =-0. 110, P = 0. 005). ConclusionsIt suggests that the eGFR decrease is associated with the severity of coronary artery stenosis, and there is a linear correlation between eGFR and Gensini score in elder people, eGFR can be used to evaluate the severity of coronary artery disease and prognosis.
