Correlation between the levels of tunlor type M2 pyruvate kinase with treatment response and prognosis in patients with non-small cell lung cancer
10.3760/cma.j.issn.1008-6315.2009.08.017
- VernacularTitle:肿瘤型M2丙酮酸激酶表达水平与非小细胞肺癌患者近期疗效及预后的关系
- Author:
Hongxu XU
;
Dong WANG
;
Lianzhou CHEN
;
Juan ZHOU
;
Futian ZHONG
;
Wentao ZENG
- Publication Type:Journal Article
- Keywords:
Non-small cell lung cancer;
Pyruvate kinase;
Tumor marker
- From:
Clinical Medicine of China
2009;25(8):830-832
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of tumor type M2 pyruvate kinase(tumor M2-PK) in nonsmall cell lung cancer (NSCLC) and their correlation with treatment response and prognosis.Methods The concentration of tumor M2-PK in plasma was detected by ELISA in 106 healthy controls and 83 NSCLC patients.The patients were followed for 24 months.Results The patients after surgical operation showed marked reduction in plasma tumor M2-PK level(13.5 U/ml vs 25.4 U/ml,P
