Evaluation of the relative efficacy of endometrial curettage for diagnosis of endometriosis by the detection of eutopic endometrial nerve fibers
10.3760/cma.j.issn.1008-6315.2009.08.039
- VernacularTitle:在位子宫内膜中神经纤维的病理检查对诊断子宫内膜异位症的价值
- Author:
Guangling GUO
;
Shuangyun CHEN
;
Chunlian ZHANG
;
Lihua FENG
;
Zhentong WEI
;
Yi LUO
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Eutopic endometrium;
Nerve fibres
- From:
Clinical Medicine of China
2009;25(8):878-879
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate endometrial biopsy and curettage in detecting small nerve fibers in eutopic endometrium for diagnosis of endometriosis.Methods Endometrial biopsies and curettings were taken in 65 women with menorrhalgia.Endometrial nerve fibers were immunohistochemically detected using the pan-neuronal marker PGP 9.5.All patients underwent laparoseopie approach.Results The specificity,sensitivity,positive and negative predictive value were 100% of endometrial biopsy and curettings for diagnosis of endometriosis.Condusions Careful endometrial biopsy combined with immunohistochemical staining for nerve fibers may be a reliable means of diagnosing or excluding endometriosis.