The clinical characteristic and prognosis of interstitial lung disease associated with polymyositis and dermatemyositis

VernacularTitle:多发性肌炎/皮肌炎合并肺间质病变的临床特征和预后
Author: Huiying GAO ; Hongyan WEN ; Xiaofeng LI ; Liyun ZHANG ; Jinli RU ; Fang LI
Publication Type:Journal Article
Keywords: Dermatomyositis; Lung disease,interstitial; Prognosis
From: Chinese Journal of Rheumatology 2009;13(8):554-556
CountryChina
Language:Chinese
Abstract: Objective To study the clinical characteristics and prognosis of interstitial lung disease (ILD) associated with polymyositis (PM) and dermatomyositis (DM). Methods The clinical data of 107 DM related ILD,and its frequency rate was 26.2%. Arthritis as the first symptom had a higher presenting rate in patients with ILD than in patients with non- ILD. Arthritis, dry cough and short of breath occurred more dyspnea presented in patients with DM-ILD, and there was serious myalgia and muscle weakness in patients More DM-ILD patients had high HBDH and AST than those in PM-ILD. High CK and CK-MB were more The 7 of 8 severe cases had DM-ILD in which 5 died of respiratory failure (death rate was 17.9% in PM/elevated ESR and CRP tend to complicate with ILD. The DM patients who have characteristic skin rashes and high AST level are prone to develop ILD. The PM patients who have high CK and CK-MB are susceptible to