Effect of chest wall radiotherapy in different manners using tissue equivalent bolus on skin and lung of cavia cobayas

VernacularTitle:豚鼠胸壁照射加组织等效膜对皮肤和肺生物效应的影响
Author: Wei HUANG ; Yaqin QU ; Xiangfu SONG ; Shixin LIU ; Xin JIANG ; Xiaojing JIA ; He GUO ; Lei YANG
Publication Type:Journal Article
Keywords: Cavia cobaya; Chest wall radiotherapy; Tissue equivalent bolus; Skin; Lung; Biological effect
From: Chinese Journal of Radiological Medicine and Protection 2009;29(4):380-382
CountryChina
Language:Chinese
Abstract: Objective To probe the influence of electron beam radiotherapy in different manners using different tissue equivalent boluses on skin and lung.Methods Adult female cavia cobayas were randomly divided into four groups as control group,fuU-time with bolus group,half-time with bolus group and without bolus group.Acute-irradiation animal models were established using electron beam in different manners with or without 0.5 cm tissue equivalent bolus.Pathological changes in lung,hair vesicle and fibroblast cell count were analyzed 40 clays after irradiation.Results The radiation dermatitis in the group with bolus was slighter than that of the group without bolus,but the radiation pneumonia was reverse.With bolus,the radiation dermatitis of haft-time group was slighter than that of full-time group.The injury repair of half-time group was more active than full-time group.Conclusions The treatment of haft-time bolus could protect lung without serious skin complications.