Detection of serum allergen specific IgE in the child with recurrent auergic purpura

VernacularTitle:过敏性紫癜患儿血清过敏原特异性IgE的检测及意义
Author: Xiujuan XIA
Publication Type:Journal Article
Keywords: Purpura; allergic; Immunoglobulin E; Allergens
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(8):1410-1411
CountryChina
Language:Chinese
Abstract: Objective To investigate the role of allergen specific IgE in the child with recurrent auergic purpura,and to detect the relation between all kinds of allergen and the disease.Methods The serum specific IgE of allergen detected by ELISA in 100 cases of the child with recurrent auergic purpura.Results 81 cases of serum allergen-specific IgE were over than 50ku/L(81%).52 cases(52%)were positive reaction to more than two kinds of allergens and 29 cases(29%)were positive reaction to one kind of allergen.Several familiar aeroallergen mixed molds (19/100),dermatophagoides(12/100)and mugwort pollens(9/100).The most familiar food fish(28/100).shrimpand crab(22/100),milk(18/100).protein(11/100).Conclusion It suggests that aeroallergens,fish,shrimp and crab play an important role in the pathogenesis of repeating child anaphy lactic purpura.Mixed molds and protein foods are important pathogens to the disease.To detect the serum specific IgE could help screen allergens,and have important role to prevent disease.