Research advancement on multiple myeloma stem cells
10.3760/cma.j.issn.1673-422X.2009.08.025
- VernacularTitle:多发性骨髓瘤干细胞研究进展
- Author:
Xiuli SUN
;
Meiyun FANG
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Stem cells;
Therapy
- From:
Journal of International Oncology
2009;36(8):629-631
- CountryChina
- Language:Chinese
-
Abstract:
Tumor stem cells have abilities of high proliferation,serf-renewal and multi-directional dif-ferentiation ;which is closely responsible for tumor' s survival and recurrence. A minor portion of myeloma stem cells exist in multiple myeloma. The research of myeloma stem cells' origins, phenotypic analyses, signaling pathways, drug resistance and other biological characteristics will do great efforts to the effective therapy of mul-tiple myeloma.