Application of hybrid artificial kidney in the treatment of uremia

VernacularTitle:组合型人工肾在尿毒症治疗中的应用
Author: Yuping CHEN ; Jingquan WU ; Hantong LI ; Yujing HUANG ; Li HUANG ; Hanying LIN
Publication Type:Journal Article
Keywords: Kidney artificial; Hemodial filtration; Uremia
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(8):1376-1377
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical efficacy and safety of hybrid artificial kidney in the treatment of patients with uremia.Methods 30 maintenance hemodialysis patients who were altered to be treated by hybrid artificial kidney(treatment group)were compared with 29 patients who were treated by hemodialysis only(control group).The amelioration of clinical symptom,remove of urea nitrogen(BUN),creatinine(Cr).Middle Molecular Substance(MMS)and variation of blood regular test were observed.Results BUN,Cr,haemoglobin level,leucocyte count and blood platelets count improved between after and before treatment(P ＜0.05),but there was no significant difference between the two groups(P ＞ 0.05).Clearance rate ofMMS(25.6%)and improvement of clinical symptoms in treatment group were better than those of control group(5.9%)and difference was statistically significant(P ＜0.05,P＜0.01).There was no serious adverse events in two groups.Conclusion Hybrid artificial kidney could remove molecular substances better and markedly improv clinical symptoms.It can make up for the shortcomings of conventional hemodialysis.