The significance of blood plasma D-Dimer level in diagnosing and treating the acute cerebral infarction patients in the community hospital
10.3760/cma.j.issn.1008-6706.2009.08.043
- VernacularTitle:急性脑梗死患者血浆D-二聚体水平变化
- Author:
Huiguang ZHANG
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Fibrin degradation prodacts
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(8):1412-1413
- CountryChina
- Language:Chinese
-
Abstract:
Objective To throagh observing the change of plasma D-Dimer level in the acute cerebral infarction patients to provide the experimental foundation for further research of pathology,physiology pathological process judgment and observation of curative effect.Methods To measure the plasma D-Dimer level by ELISA in 71 cases of acute wrebral infarction patients and 64 healthy controls.Results The plasma D-Dimer level in the acute cerebral infarction patients in acute period was 72h(1.54 ±0.91)mg/L、7d(1.32 ±0.86)mg/L significantly higher than 15d (0.49±0.31)mg/L30d(0.32±0.14)mg/L at resume period patients and(0.31 ±0.81)mg/L at normal controls and dropped in resume period(t =2.576,t =2.807,P<0.01).They had significant difference.Conclusion The results indicate that acute cerebral infarction is in the manifestation of hyper coagulation,plasma D-Dimer measuring was valuable for pathological process judgment and observation of curative effect of acute cerebral infarction.