Distribution and drug resistance of pathogens in cancer patients with nosocomiai infection

VernacularTitle:恶性肿瘤患者医院感染病原菌及耐药特征分析
Author: Yanping RUAN ; Wenying ZHANG ; Caiping MAO ; Mingli WANG
Publication Type:Journal Article
Keywords: Carcinoma; Nosocomial infection; Pathogen; Drug resistance
From: Chinese Journal of Clinical Infectious Diseases 2009;2(4):209-213
CountryChina
Language:Chinese
Abstract: Objective To investigate the distribution and drug resistance of pathogens in cancer patients with nosocomial infections. Methods Pathogens isolated from cancer patients with nosocomial infections in Zhejiang Cancer Hospital from 2004 to 2008 were analyzed. Results Totally 3454 strains of pathogens were isolated, including 1900 strains of Gram-negative bacilli (55.0%), 838 strains of fungi (24.3%), and 716 strains of Gram-positive bacteria (20.7%). Pathogenic bacteria Escherichia coli and Candida albicans were isolated mainly from surgical wound, urinary tract, respiratory tract and oral cavity. The drug resistant rates for Gram-negative Escherichia coli and Gram-positive staphylococci were high, and Candida albicans was sensitive to all antifungal drugs. Conclusion Opportunistic pathogens account for most nosocomial infections in cancer patients, and some of them are of high-level resistance to antimicrobial agents.