The clinical value of MMP-9 and PIIINP in diagnosis of acute myocardial infarction

VernacularTitle:急性心肌梗死患者血清基质金属蛋白酶-9和前胶原氨基末端肽水平变化
Author: Junwei LIU
Publication Type:Journal Article
Keywords: Myocardial infarction; Matrix metalloproteinase 9; Procollagen n-endopeptidase
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(8):1387-1388
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical value of MMP-9 and PIIINP in diagnosis of acute myocardial infarction.Methods To retrospective analyze MMP-9 and PIIINP In 76 cases patients with acute myocardial infarction ,when prophase and anaphase of treatment in our hospital.Results The MMP-9(191.6 ±38.5)μg/L and PIIINP(8.9 ±1.8)μg/L of observation group treatment prophase were higher than control group[(85.6 ±33.2)μg/ L,(3.5 ±1.5)μg/L],(t = 13.01,14.55,P ＜ 0.05),which were obviously different between treatment anaphase 3d,7d,14d MMP-9[(170.2 ±30.2)μg/L,(123.6 ±32.7)μg/L,(90.2 ±30.2)μg/L]and PIIINPf(6.9 ±1.7)μg/L,(5.2 ±1.6)μg/L、3.7 ±1.8)μg/L]were lower than treatment prophase(t = 12.63,9.58,5.36,5.01 ,18.0,17.8,all P＜0.05);the MMP-9(90.2 ±30.2)μg/L and PIIINP(3.7 ±1.8)μg/L were remove in treatment anaphase 14d,which had no difference between treatment anaphase 14d and treatment prophase(t=0.69,0.54,all P＞ 0.05).Conclusion The MMP-9 and PIIINP were higher diagnostic value in clinical diagnosis acute myocardial infarction,which was worth to be used.