Gastrointestinal Dysfunctions in Parkinson's Disease.
- Author:
Joong Seok KIM
1
;
Hey Young SUNG
Author Information
- Publication Type:Review
- Keywords: Parkinson's disease; Gastrointestinal symptoms; Enteric nervous system
- MeSH: Constipation; Deglutition Disorders; Enteric Nervous System; Gastrointestinal Tract; Mortality; Parkinson Disease*; Weight Loss
- From:Journal of the Korean Neurological Association 2015;33(4):247-251
- CountryRepublic of Korea
- Language:Korean
- Abstract: Gastrointestinal symptoms are a frequent but usually underreported constituent of the clinical spectrum of Parkinson's disease (PD), and they contribute significantly to the disease-related morbidity and mortality. Virtually all parts of the gastrointestinal tract can be affected, even in the premotor stage. Weight loss, salivary excess, dysphagia, nausea/gastroparesis, constipation, and anorectal dysfunction can all occur. Gastrointestinal symptoms may result from the involvement of either the central or enteric nervous system in the disease process, or be a side effect of antiparkinsonian medications. Awareness of the various gastrointestinal manifestations of PD can facilitate the prompt recognition of and effective therapeutic intervention for these potentially distressing symptoms.
