Chemoembolization with MMC-Iipiodol or ADM-lipiodol mixture for the treatment of bronchogenic carcinoma

VernacularTitle:化疗栓塞术治疗肺癌临床研究
Author: Kun LU ; Junwei ZHANG ; Bing WANG
Publication Type:Journal Article
Keywords: Lung neoplasms; Chemoembolization; therapeutic; Piodized oil
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(8):1390-1391
CountryChina
Language:Chinese
Abstract: Objective To study the clinical value of transbronchial arterial chemoembolization with MMC-li piodol or ADM-lipiodol mixture in the treatment of lung cancer.Methods In this study 32 cases with lung cancer,bronchial arteriography were adopted to identify the tumor-feeding branch.After perfusing 500～1000mg 5-Fu and 60 ～80mg CDDP through microcatheter,embolization with the mixture of 3 ～10ml lipiodol and 20mg MMC or 40mg ADM was performed.Results Short-term effectiveness;complete response(CR)was achieved in 1 case,while partial response(PR)in 19 cases,steady disease(SD)in 11 cases and process disease(PD)in 1 case.The total effectiverate (CR plus PR)was up to 62.5%(20/32).Complications included S cases of the chest pain and 2 cases of the chest wall epidermis pain,which were relieved after symptomatic management.1 case produced spinal injury,which was partially recovered after symptomatic management.Conclusion Transbronchial arterial chemoembolization with MMC-li piodol or ADM-lipiodol mixture has good short-term effect in the treatment of lung cancer.The procedure should be carried out carefully to avoid severe complications.