Sequencing VP4, VP7, NSP1, NSP4 genes of human Rotavirus strain G1P8
- Author:
Nguyen Thanh Thuy
- Publication Type:Journal Article
- Keywords:
Amino acids;
Sequence;
NSP4 genes;
Human rotavirus;
Strain G1P8;
Rotavirus;
Nucleotides;
- MeSH:
Rotavirus;
Human;
Genes;
Child
- From:Journal of Preventive Medicine
2005;15(6):27-32
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Rotavirus is the main cause of acute viral gastroenteritis in children under 5 years old. The study is to sequence nucleotides and amino acids of VP4, VP7, NSP1, and NSP4 genes of 5 passages of human rotavirus strain G1P8. The number of nucleotide mutations of VP4, VP7, NSP4 genes occuring among the passages were 3, 1, and 3, respectively. All these mutations resulted in changes in amino acid composition. No mutation was found in NSP1 gene.