Effects of pioglitazone on leptin-induced proliferating cell nuclear antigen and leptin receptor expression of vascular smooth muscle cells
10.3760/cma.j.issn.1000-6699.2009.04.007
- VernacularTitle:吡格列酮对瘦素诱导的血管平滑肌细胞PCNA及瘦素受体表达的影响
- Author:
Fang WANG
;
Xianghua MA
;
Jie SHEN
;
Yaqin DING
;
Xiaoqing YUAN
- Publication Type:Journal Article
- Keywords:
Pioglitazone;
Vascular smooth muscle cells;
Leptin;
Leptin receptor;
Proliferating cell nuclear antigen
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(4):384-385
- CountryChina
- Language:Chinese
-
Abstract:
leptin-induced VSMCs proliferation as well as expression of PCNA and OB-R at both mRNA and protein levels. The maximum effect was at 100 μmol/L(P<0.01).
