Gastrointestinal stromal tumors of the stomach

VernacularTitle:胃间质瘤的临床病理特征和预后相关因素分析
Author: Tiansuo ZHAO ; Huikai LI ; Xiuchao WANG ; He REN ; Jihui HAO
Publication Type:Journal Article
Keywords: Gastrointestinal stromal tumors; Pathology; clinical; Prognosis
From: Chinese Journal of General Surgery 2009;24(9):689-691
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical characteristics of gastrointestinal stromal tumor (GIST) of the stomach and to analyze the corresponding prognostic factors. Methods We retrospectively reviewed the clinical data of 121 patients in our hospital from March 1996 to March 2008. Gender、age、tumor size and histological type were analyzed. Results For these 121 cases the median survival time is 73.2 months. The overall 1-、3-、and 5-year survival rates were 82%, 59% and 50% respectively. The tumor-free survival rates for 1-、3-、and 5-yeas were 65%, 46% and 33% respectively. Cox univariale analysis revealed that gender、tumor size、organ involvement and recurrence were factors impacting prognosis. Cox multivariate analysis revealed that gender、tumor size、organ involvement、recurrence were prognostic factors for gastric GIST. Conclusions Male sex、tumor size (> 10 cm) and involvement of organ were independent indicators for a poor prognosis in patients with primary malignant gastric GIST.