Evaluation of the sterilizing efficiency on absorbable poly-L-lactide screws with two sterilants
10.3760/cma.j.issn.1673-4181.2009.04.003
- VernacularTitle:左旋聚乳酸可吸收骨钉两种灭菌法效果评价
- Author:
Yuexiong YANG
;
Weihong YANG
;
Jing LI
- Publication Type:Journal Article
- Keywords:
Absorbable poly-L-laetide screws;
Ethylene oxide;
60Co-γ radial;
Sterilization
- From:
International Journal of Biomedical Engineering
2009;32(4):201-205
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the sterilizing efficiency ofabscrbable poly-L-lactide (PLLA) screws sterilized with ethylene oxide and 60Co-γ radial. Methods One group of PLLA screws was sterilized in the ethylene oxide sterilization ease. In order to eliminate the rudimental ethylene oxide, the sterilized screws was put in the air for five days. The other group of PLLA screws was sterilized with 60Co-γ radial with absorbable dose of 15 kGy. Then all sterilized screws were characterized. Results Compared with the primal bend intensity of the PLLA screws, the bend intensity of sterilized screws did not descend remarkably (P＞0.05). Compared with the primal molecular weight of the PLLA screws, the molecular weight of screws with 60Co-γ radiation sterilization re-markably decreased 11%. It indicated that the material had degraded. The molecular weight of screws with ethylene oxide sterilization ordy decreased 3%. It indicated that the material didn't degrade obviously. Conclusion Ethylene oxide sterilization is a better way for sterilizing absorbable PLLA screws.
