Relationship between aryl hydrocarbon receptor and tumor
10.3760/cma.j.issn.1673-4203.2009.09.022
- VernacularTitle:芳香烃受体与肿瘤的关系
- Author:
Chun ZANG
;
Fang LU
;
Xiaofeng LI
;
Huaping LIANG
- Publication Type:Journal Article
- Keywords:
aryl hydrocarbon receptor;
tumor
- From:
International Journal of Surgery
2009;36(9):640-643
- CountryChina
- Language:Chinese
-
Abstract:
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor, which can be ac-tivated by the binding of exogenous atyl hydrocarbon chemicals, then increase many metabolic enzymes and their activity, and oncogenic products of metabolism increase, ultimately resulting in occurrence of tumor. Herein, we mainly review the fundamental concept of AHR and its relationship with tumor.
