Protein transduction technique in differentiation of pancreatic stem cell
10.3760/cma.j.issn.1673-4203.2009.09.017
- VernacularTitle:蛋白转导技术在胰腺干细胞分化中的应用
- Author:
Jie MA
;
Lin FANG
- Publication Type:Journal Article
- Keywords:
protein transduction;
pancreatic stem cells;
differentiation
- From:
International Journal of Surgery
2009;36(9):623-626
- CountryChina
- Language:Chinese
-
Abstract:
As a new biotechnology, protein transduction connects the target fragment with biology active and protein transduction domain, and transducer it in to cells, exert its biological effects. Protein transduc-tion domain is a small molecule peptide, not only the protein transduction domain can penetrate through cell membrane, but could maintain the activity of its fusion protein. Protein transduction is an emerging biology technology, it has been applied into all aspects of cell gene regulation since its invention. In this article, we take Tat, Pdx-1 and Beta/NeuroD for instance and review the application of transduction protein in the dif-ferentiation of pancreatic stem cell.
