Clinical diagnosis and treatment for recurrence and progress of relieved myasthenia gravis after thymecto-my
10.3760/cma.j.issn.1008-6315.2009.10.025
- VernacularTitle:重症肌无力胸腺切除术后病情反复的临床诊断与治疗体会
- Author:
Xuguang WANG
;
Kunpeng YANG
;
Huashan SHOU
;
Jin ZHANG
;
Chengyu SHE
- Publication Type:Journal Article
- Keywords:
Myasthenia gravis;
Thymectomy
- From:
Clinical Medicine of China
2009;25(10):1073-1075
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the experience of clinical diagnosis and treatment for recurrence and progress of relieved myastbenia gravis after thymectomy. Methods 22 recurrent and progressive after relieved pa-tients with myasthenia gravis who underwent thymectomy were retrospectively analyzed. The remission therapy was conducted with combined glucocorticoid and anticholinesterase and its effectiveness was estimated. Results It was 1,17,4 as better Osserman scale Ⅰ , Ⅱ , Ⅲ respectively before operation but 15,6,1 as better Osserman scale Ⅱ , Ⅲ, Ⅳ respectively in recurrence and progress of relieved myasthenia gravis after thymectomy besides 6 with myas-thenic crisis. Complete remission and partial remission were gained in 9 patients and 12 patients respectively. There was 1 hospital-death. Conclusions Recurrence and progress can occur in any patient of relieved myasthenia gravis after thymectomy. Bulbar myasthenia gravis is usually presented as dysphagia. Reasonable administration of glucocor-tieoid could improve majority of recurrence and progress of relieved myasthenia gravis after thymectomy but responses poorly to the anticholinesterases.
