Clinical obser ration of interferon α-2b on the treatment of viral keratitis:476 cases study

VernacularTitle:干扰素α-2b治疗病毒性角膜炎476例疗效观察
Author: Yan LIU ; Xiaolu SHEN ; Xiaodong SUN ; Xun XU
Publication Type:Journal Article
Keywords: Interferon α-2b; Keratitis
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(9):1578-1579
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of interferon on the treatment of virus keratitis. Meth-ods Review and analysis was made of 476 patients with virus keratitis who was treated with high concentration of an-ti-virus eyedrops and one million unit of α-2b interferon, the clinical safety and effect was evaluated. Result The total cure rate was 59. 1%, and the type from high to low is interstitial、endothelial、epithelial and the total cornea. The total recurrence rate is 23.5% ,and the type from high to low is epithelial,the total cornea,endothelial and inter-stitial. The incidence rate of the adverse effect is 10. 7%. Condusion Systemic administration of interferon has a direct anti-virus effect, and it can raise the cure rate of virus keratitis as well as decrease recurrencerate. One million unit of interferon has a high clinical safety and effect.