The Experimental Rearch of Silkworm Cocoon/ Portulaca Oleracea on the Glucose and Lipid Metabolism to type 2 Diabetic Rats
10.3760/cma.j.issn.1673-4246.2009.05.004
- VernacularTitle:蚕茧、马齿苋对2型糖尿病大鼠糖脂代谢影响的实验研究
- Author:
Shuqin WANG
;
Aiguo MA
;
Yongye SUN
;
Xuelong LI
;
Xuemei YI
;
Minxiu YAO
- Publication Type:Journal Article
- Keywords:
Silkworm Cocoon;
Portulaca oleracea;
Type 2 Diabetis;
Insulin Resistance
- From:
International Journal of Traditional Chinese Medicine
2009;31(5):395-396
- CountryChina
- Language:Chinese
-
Abstract:
Objective To approach the effect of Silkworm Cocoon,Portulaca oleracea on the glucose and lipid metabolism to type 2 Diabetic rats. Methods type 2 diabetic rat models induced by STZ were randomly divided into diabetes model group,Silkworm Cocoon group,Portulaca oleracea group,Silkworm Cocoon+Portulaca oleracea group,and normal contrast group,after eight weeks' intervention,We analyze blood glucose(GLU), triglyeeride(TG), SOD, GSH, MDA, calculate, the indexes of insulin resistance (HOMA-1R). Results compared with diabetes model group, the GLU in Silkworm Cocoon+Portulaca oleracea group decrease 53.3%(P<0.01) : The TG decrease 44.1%(P<0.05). the Homa-IR decrease groups has no statistic difference. Conclusion The mixture group can obviously improve the glucose and lipid metabolism、 relieve insulin resistance、 significantly increase antioxidatian、 decrease the products oflipid peroxide.
