Effect of devated plasma lipoprotein (a) on restenosis after stent implantation
10.3760/cma.j.issn.1008-6315.2009.10.006
- VernacularTitle:高脂蛋白a血症对冠状动脉支架术后再狭窄的影响
- Author:
Chunying WEI
;
Yunfeng WEI
;
Menghong WANG
;
Zeqi ZHENG
;
Jingtian PENG
;
Jun HUANG
;
Bingong LI
;
Yuan WEN
;
Zhiyong WU
- Publication Type:Journal Article
- Keywords:
Lipoprotein (a);
Coronary heart disease;
Instent restenosis;
Stent
- From:
Clinical Medicine of China
2009;25(10):1027-1029
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between plasma lipoprotein (a) [LP (a)] concentra-tion and in-stent restenosis after coronary stent implantation. Methods 152 patients with successful elective coro-nary stont implantation and percutancous transluminal coronary angioplasty (PICA) undergoing foUow-up angiogra-phy were retrospectively analyzed. These patients were divided into restenosis group( n = 29) and no-restenosis group (n = 123 ). The serum LP (a) levels of all patients were also investigated. The general clinical data were analyzed. Multivariate logistic regression was used for statistical analysis. Results We compared the serum Lap (a) levels, smoking and diabet in the two groups, and there was a statisticaLly significant difference between the restenosis group and no-restenosis group(P<0.05). Multivariate logistic regression showed that the elevation of Lap (a) level re-mained as an independent predictor of restenosis (RR =2. 648,95% CI 1. 066-6. 575,P <0. 05). Other risk fac-tors,such as smoking(P =0.023) ,diabet(P =0. 036) and the type of stent(P = 0.011 ) were also correlated with restenosis. Conclusions High plasma LP (a) concentration is an independent predictor of stent restenosis after stent implantation.
