The diagnostic value of adenosine myocardial perfusion single photon emission computed tomography in elderly patients with coronary artery disease
10.3760/cma.j.issn.0254-9026.2009.10.004
- VernacularTitle:腺苷心肌灌注断层显像诊断老年人冠心病的价值
- Author:
Shujie JIA
;
Nanye WANG
;
Xizhi WANG
;
Shuhua MI
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Adenosine;
Coronary angiography
- From:
Chinese Journal of Geriatrics
2009;28(10):812-815
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of adenosine stress ~(99m)Tc-MIBI myocardial perfusion single photon emission computed tomography (ECT)in elderly patients with coronary artery disease (CAD). Methods Fifty-three patients aged ≥60 years without the history of myocardial infarction were included in the research. The average age of the patients was(65.5±6.5) years (60-78 years old). All patients underwent adenosine stress ~(99m)Tc- MIBI myocardial perfusion single photon ECT and coronary angiography (CAG) within 2 months, and the results were compared. Results Compared with CAG, the sensitivity, specificity, positive predictive value, negative predictive value and accurate index of ECT were 73.7%, 90.9%, 94.3%, 80.0% and 62.3%, respectively. The specificity for left anterior descending artery, left circumflex artery and right coronary artery of ECT were 90.9%, 85.7% and 100%, respectively, and the positive predictive values were 73.5%, 77.3% and 72.0%, respectively. Conclusions Adenosine is a strong vasodilator and it has multiple effects on cardiovascular system. Combination of angiocardiography and myocardial perfusion imaging can be used in diagnosis of coronary artery disease. ECT is a noninvasive, convenient and low cost method and plays an important role in diagnosing, directing treatment and judging prognosis of CAD in the elderly patients.
