Advance in relationship between autophay and tumor
10.3760/cma.j.issn.1673-4203.2009.09.021
- VernacularTitle:自噬与肿瘤关系的研究进展
- Author:
Ruidan ZHUANG
;
Junjian LI
;
Wei CHEN
;
Tingbo LIANG
- Publication Type:Journal Article
- Keywords:
autophagy;
tumor;
signal pathway
- From:
International Journal of Surgery
2009;36(9):636-640
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is known as cellular degradation of long-lived proteins and organelles, by a double-membranound structure fusing with the lysosome, for recycling intraceUular constituents and reusing nutri-tion. Defective autophagy is closely correlated with tumorigenesis and tumor progress. There are crosstalks between autophay associated/regulative genes and oncogene/anti-oncogene. More over, regulative autophagic cell death may lead to an novol way for cancer therapy.
