Hand ,foot and mouth disease in mainland China: an update on epidemic situation, diagnosis and treatment
10.3760/cma.j.issn.1673-4912.2011.01.001
- VernacularTitle:手足口病在中国大陆的流行现状及诊治进展
- Author:
Suyun QIAN
- Publication Type:Journal Article
- Keywords:
Hand,foot and mouth disease;
Epidemiology;
Diagnosis;
Treatment
- From:
Chinese Pediatric Emergency Medicine
2011;18(1):1-3
- CountryChina
- Language:Chinese
-
Abstract:
Hand,foot and mouth disease has become more widespread in mainland China in recent years and has shown an increasing trend in the annual prevalence, which has attracted considerable attention as a major public health problem. Enterovirus 71 (EV71) and coxsackievirus A16 (Cox A16) are major pathogens. Ninety-five percent of severe patients and death cases were younger than 3 years old. Unfortunately,there is no effective anti-enteroviral drug for hand, foot and mouth disease, therefore symptomatic treatment and supportive care remain as the mainstream therapy. Intravenous immunoglobulin (IVIG) is expected to be used in recent clinical trials, but its efficacy remains to be seen. Glucocorticoid therapy is still controversial in critical cases. EV71 vaccine is under development; however, it takes time to launch a mass vaccination. Multidisciplinary prospective, multicentral study is essential to control the spread of hand, foot and mouth disease and to tackle the problems of diagnosis and treatment.
