Effect of general anesthesia used in cesarean section on maternal-neonatal outcome of pregnancy complicated with severe thrombocytopenia
10.3760/cma.j.issn.0529-567x.2009.09.008
- VernacularTitle:剖宫产术时全身麻醉对妊娠合并严重血小板减少产妇母儿结局的影响
- Author:
Jun WEI
;
Guoli HU
;
Meiying LIANG
;
Shanmi WANG
- Publication Type:Journal Article
- Keywords:
Cesarean section;
Thrombocytopenia;
Pregnancy complications;
hematologic;
Anesthesia;
general;
Pregnancy outcome
- From:
Chinese Journal of Obstetrics and Gynecology
2009;44(9):665-668
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of general anesthesia on pregnancy women with thrombocytopenia and neonate during cesarean section(CS). Methods Sixty-five singleton pregnant women with low platelet count (<50×10~9/L) and gestation >35 weeks were allocated into general anesthesia group (35 cases) and local anesthesia group (30 cases) randomly. The time from skin incision to fetal delivery, the oxyhemoglobin saturation(SO_2) before and after anesthesia, the blood loss during operation, Apgar scores at 1 min, birth weight, umbilical cord blood gas analysis were recorded. Results The mean time from anesthesia induction to fetal delivery was (9.7±3.5) minutes in general anesthesia group. The time from skin incision to fetal delivery in general anesthesia group [(7.7±2.5) minutes] was shorter than that in local anesthesia group [(12.5±3.0) minutes, P<0.01], while the operation time had no significant differences. There were no significant difference for the value of SO_2 before and after general anesthesia or local anesthesia(P>0.05). There was no significant difference for the blood loss [(471±245)ml vs. (452±213 )ml, P>0.05], Apgar scores at 1 minute, birth weight and umbilical cord blood gas analysis between the two groups (P>0.05). There had two infants with blue asphyxia in local anesthesia group while no infant with asphyxia in general anesthesia group. Conclusion General anesthesia is safe to pregnant women with thrombocytopenia during CS.
