Experimental Study on the Anti-contact Dermatitis Efficacy and Antiviral Effect of JingFuYe
10.3760/cma.j.issn.1673-4246.2009.05.006
- VernacularTitle:净肤液对接触性皮炎及抗病毒作用的实验研究
- Author:
Junqing HE
;
Yushan LI
;
Shuying LEI
;
Shangzhou CHEN
;
Jun LV
;
Jun HAO
- Publication Type:Journal Article
- Keywords:
JingFuYe;
Contact dermatitis;
Mice;
Herpes simplex virus;
Guinea pig
- From:
International Journal of Traditional Chinese Medicine
2009;31(5):399-400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the antiviral effect and anti-contact dermatitis efficacy of JingFuYe. Methods Made contact dermatitis mice model by DNFB, measured the central thickness of mice left ear in each medication group and adopted the ABC immunohistochernical method to detect the number of Langerhan spcell(LCs). Infect guinea pig vaginal by HSV-2. Changes of symptoms were evaluated by Symptom score method. Detect the number of HSV-IgG and IgM in guinea pig serum. Results Compared with the control group, the ear thickness difference and the number of LCs in the experimental group were significantly reduced. JingFuYe have inhibitive effect to the Lesions caused by HSV-2 vaginal infection in guinea pig On different extents. Conclusion JingFuYe has inhibitive function to the murine experimental contact dermatitis and anti-virus effects.