The roles of vascular endothelial growth factor in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2009.09.012
- VernacularTitle:血管内皮生长因子在脑缺血中的作用
- Author:
Guofeng WANG
;
Renliang ZHAO
- Publication Type:Journal Article
- Keywords:
vascular endothelial growth factor;
neovasculafization,physiologic;
neuroprotective agents;
neurogenesis;
cerebral ischemia
- From:
International Journal of Cerebrovascular Diseases
2009;17(9):705-709
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelial growth factor(VEGF)is a major angiogenic factor that regulates multiple endothelial cell functions. After cerebral ischemia, VEGF not only promotes vascular endothelial proliferation and migration. involving in angiogenesis and increasing vascular permeability, but also plays important roles in both neuroprotection and neurogenesis. This article reviews the roles of VEGF in ischemic cerebral injury.