Recent progress in establishment and application of animal models of cerebral arteriovenous malformation
10.3760/cma.j.issn.1673-4165.2009.09.014
- VernacularTitle:脑动静脉畸形模型的建立和应用新进展
- Author:
Jian LI
;
Yaoyu YU
;
Li GAO
;
Guodong GAO
- Publication Type:Journal Article
- Keywords:
intracranial arteriovenous malformation;
disease models,animal
- From:
International Journal of Cerebrovascular Diseases
2009;17(9):716-720
- CountryChina
- Language:Chinese
-
Abstract:
A cerebral arteriovenous malformation is a congenital disorder characterised by an abnormal connection between the arteries and the veins in the brain. It causes intracranial bleeding, seizures, severe headache, and progressive neurological deficits. The therapeutic strategies were usually established on the basis of clinical experiences due to lack of ideal models of arteriovenous malformation in the past .In order to further increase the success rate of surgery and decrease complications, this article reviews the advances in establishment and application of animal models of cerebral arteriovenous malformation in recent years.