Nasogastric enteral nutrition for severe acute pancreatitis:meta-analysis of clinical trials

VernacularTitle:重症急性胰腺炎经鼻胃管营养支持的Meta-分析
Author: Zhongfang YAN ; Yumei QI ; Wei LU ; Yi XIE
Publication Type:Journal Article
Keywords: Severe acute pancreatitis; Enteral nutrition; Nasogastric tube; Meta-analysis
From: Chinese Journal of Clinical Nutrition 2009;17(5):271-274
CountryChina
Language:Chinese
Abstract: Objective To assess the safety and effectiveness of nasegastric enteral nutrition (NGEN) in patients with severe acute pancreatitis (SAP).Methods A meta-analysis of all the relevant clinical trials was performed.Clinical trials were identified from the following electronic databases:Medline,EMBASE,the Cochrane Controlled Trials Register,and Chinese Bio-medicine Database.The search was undertaken in October 2008.The literature quality was evaluated with Cochrane Handbook 5.0.The statistical analysis was performed by RevMan 4.2 software.Results Four trials involving 157 patients were included.The combined results showed that no significant differences in the safety and tolerance between nasogastric and conventional routes in patients with SAP.Conclusions Currently available data show early NGEN appears to be effective,safe,and tolerable in patients with SAP.However,more large-scale high-quality trials are required to further elucidate this topic.