The human papilloma virus in endometrium cancer and its clinical significance
10.3760/cms.j.issn.1008-6706.2009.10.016
- VernacularTitle:人乳头状瘤病毒在子宫内膜癌组织中的检测
- Author:
Yingzi ZHANG
;
Yuzhen HAN
;
Yong GAO
;
Hong MENG
;
Chunying QI
- Publication Type:Journal Article
- Keywords:
Papillomavirus infections;
Endometrial neoplasms;
In situ hybridization
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(10):1757-1758
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate human papilloma virus(HPV) infection in normal endometrium, atypi-cal hyperplasia of endometrium and endometrial carcinoma. Methods By the nucleic acid hybridization,we detected 28 pairs of endometrial carcinomas, 21 pairs of atypical hyperplasia of endometrium. Normal endometrium from 16 pa-tients with uterine myomas were as control. Results HPV16/18 DNA was detected in 25 endometrial carcinoma and 2 atypical hyperplasia of endometrium and 1 normal endometrium. Conclusions Endometrial carcinoma HPV16/18 DNA were significantly higher than those infected with atypical endometrial hyperplasia and normal endometrium. Note the occurrence of endometrial cancer,the development may be associated with HPV infection.
