Effect of blood pressure management on perihematomal edema in patients with hypertensive intracerebral hemorrhage
10.3760/cma.j.issn.1673-4165.2009.10.004
- VernacularTitle:血压管理对高血压脑出血患者血肿周围水肿的影响
- Author:
Pan LIN
;
Gang WU
;
Xing CHEN
;
Qingxiao SHI
- Publication Type:Journal Article
- Keywords:
cerebral hemorrhage;
brain edema;
hypertension;
calcium channel blockers;
angiotensin-converting enzyme inhibitors
- From:
International Journal of Cerebrovascular Diseases
2009;17(10):742-746
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of blood pressure management on perihematomai edema in patients with acute hypertensive intracerebral hemorrhage. Methods The retrospective research method was used to conduct logistic regression analysis for the factors of age, number of days, antihypertensive drugs, dehydrating agents, and blood pressure in inpatients with hypertensive intracerebral hemorrhage from June 2005 to December 2007. Results Multivariate analysis found that both amlodipine (OR = 0. 208, 95% CI 0. 063-0. 684) and angiotensin-converting enzyme inhibitor (ACEI) (OR = 0. 280, 95% CI 0. 085-0. 920) were the protective factors for perihematomal edema; both the course of 10 to 20 days (OR =7.413, 95% CI 1. 362-40. 360) and poorly controlled diastolic blood pressure (OR = 6. 449, 95% CI 1. 011-41. 145) were the risk factors for perihematomal edema. Conclusions Amlodipine and ACEI may lower the risk of perihematomal edema in intracerebral hemorrhage, while the poorly controlled diastolic blood pressure and the course of 10 to 20 days are the risk factors for perihematomal edema.
