The biological characters of hepatic stellate cell and its regulation of tumor microenvironment
10.3760/cma.j.issn.1673-4203.2009.11.013
- VernacularTitle:肝星状细胞的生物学特性及其调节肿瘤微环境的研究进展
- Author:
Weiying ZHU
;
Jianbin XIANG
;
Xueli ZHANG
- Publication Type:Journal Article
- Keywords:
hepatic stellate cell;
neoplasm;
microenvironment
- From:
International Journal of Surgery
2009;36(11):757-760
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic stellate cells(HSCs) are the mesenchymal cells in the liver. In the process of tumori-genesis and metastasis, the interactions between HSCs and tumor ceils play an important role in promoting tumor invasion through extracellular matrix remodelling. Here we review the latest investigative advances a-bout the tumor-stromal interactions.