Research progress of relationship between claudin protein and pancreatic neoplasms
10.3760/cma.j.issn.1673-4203.2009.11.020
- VernacularTitle:紧密连接蛋白Claudins与胰腺肿瘤关系的研究进展
- Author:
Mingjie XIA
;
Taiping ZHANG
;
Yupei ZHAO
- Publication Type:Journal Article
- Keywords:
ligandin;
pancreatic neoplasms;
claudin protein
- From:
International Journal of Surgery
2009;36(11):778-781
- CountryChina
- Language:Chinese
-
Abstract:
claudin protein is the major component of tight junctions complex between cells,which plays an important role in cells junction and adhesion. Its specific expression in different tissues directly affects the biological behavior of tumor cells. In pancreatic tumors, the claudin's expression provides an important refer-ence for the diagnosis and treatment of tumors. In addition, claudin are involved in the proliferation and ap-optosis of tumor cells. In the treatment of tumors, claudin-mediated targeting therapy has great prospects forthe same.
