Severe pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome:analysis of 31 cases

VernacularTitle:重度子痫前期与子痫并发可逆性后部白质脑病综合征31例临床分析
Author: Yong WANG ; Chun YANG ; Hong CHANG ; Kun YANG ; Dexian ZHENG
Publication Type:Journal Article
Keywords: Eclampsia; Cerebrovascular disorders; Treatment outcome
From: Chinese Journal of General Practitioners 2009;8(11):796-798
CountryChina
Language:Chinese
Abstract: Objective To explore clinical characteristics of severe pre-eclampsia and eclampsia complicated with reversible posterior leukoencephalopathy syndrome(RPLS).Methods Clinical data of 31 cases of severe pre-eclampsia and eclampsia complicated with RPLS were studied retrospectively.ResulIs These 31 cases with RPLS accounted for 48% of those with eclampsia,.and all presented with hypertension,headache and disturbalice of vision,24 cases with seizure episodes,19 cases with nausea and vomiting and 13 with continuous dysphoria after seizure.Neuroradiologic findings showed edema predominantly in the bilateral posterior cerebral white matter,especially in occipital-parietal lobe,with low density lesions in CT and long T1 and T2 signals in brain MRI. Conclusions Severe pre-eclampsia and eclampsia tended to complicate with RPLS,presenting severe hypertension,headache,disturbance of vision and recurrent seizure as major clinical manifestations.