Granulocyte-maerophage colony-stimulating factor for ischemic cerebrovascular disease
10.3760/cma.j.issn.1673-4165.2009.10.013
- VernacularTitle:粒细胞-巨噬细胞集落刺激因子治疗缺血性脑血管病
- Author:
Hairong DONG
;
Ye HUA
;
Xinsheng DING
- Publication Type:Journal Article
- Keywords:
granulocyte-macrophage colony-stimulating factor;
cerebral ischemia;
cerebrovascular disorders;
neuroprotective agents
- From:
International Journal of Cerebrovascular Diseases
2009;17(10):783-786
- CountryChina
- Language:Chinese
-
Abstract:
Granulocyte macrophage-colony stimulating factor (GM-CSF) is a muhifunctional growth factor. It stimulates the proliferation, differemiation and maturity of hematopoietic progenitor cell (HPC), and transfers from bone marrow to periphery, inducing multiple cell proliferation or differentiation. In recent years, some studies have indicated that GM-CSF plays an important role in anti-apoptosis, inducing neuronal differentiation and angiogenesis, which will he a new supplement to the treatment of ischemic cerebrovascular disease. This article reviews the effects of GM-CSF in the treatment of ischemic cerebrovascular disease.
