Advances of eIF4E in breast cancer research
10.3760/cma.J.Issn.1673-422X.2009.11.017
- VernacularTitle:真核起始因子 4E 在乳腺癌中的研究进展
- Author:
Feifei ZHOU
- Publication Type:Journal Article
- Keywords:
eIF4E;
Breast neoplasms;
Prognosis;
Therapy
- From:
Journal of International Oncology
2009;36(11):850-852
- CountryChina
- Language:Chinese
-
Abstract:
Eukaiyotic translation initiation factor 4E(eIF4E) is a key factor initiate eukaryotic transla-tion. eIF4E has significant correlation with the carcinogenesis, cancer development and invasion, etc. Recent studies in breast cancer show that eIF4E is an important prognostic factor and associated with sensitivity of breast cancer cells to radiotherapy. eIF4E expression has a potential contribution to therapeutic strategy mak-ing, meanwhile, it is a promising effective target of breast cancer treatment.
