Relation between cytokeratin and tumor
10.3760/cma.j.issn.1673-422X.2009.11.012
- VernacularTitle:细胞角蛋白与肿瘤的关系
- Author:
Xiuli HOU
- Publication Type:Journal Article
- Keywords:
Keratin;
Neoplasms;
Phosphorylation;
Mutation
- From:
Journal of International Oncology
2009;36(11):836-839
- CountryChina
- Language:Chinese
-
Abstract:
Cytokeratins can maintain the morphous and function of normal cells. Clinically, cytokera-tins are used to diagnose several tumors as tumor markers. Recently, numerous studies indicate that the abnor-mal expression, mutation in the site of phosphorylation and hyperphosphorylation have relationship with the mechnism of tumorigenesis. Reseach of the relationship is important for the diagnosis, therapy and prognosis of tumor.
