Relation between inhibitor of apoptosis protein Apollon and tumor
10.3760/cma.j.issn.1673-422X.2009.11.011
- VernacularTitle:凋亡抑制蛋白Apollon与肿瘤的相关性
- Author:
Yuanyuan LIU
- Publication Type:Journal Article
- Keywords:
Apollon;
Neoplasms;
inhibitor of apoptosis proteins
- From:
Journal of International Oncology
2009;36(11):833-836
- CountryChina
- Language:Chinese
-
Abstract:
Apollon is a member of inhibitor of apoptosis proteins. It can inhibit apoptosis through inter-action with Smac, HtrA2 and caspase. Apollon is highly expressed in a variety of tumors, such as leukemia, breast cancer, brain cancer, carcinoma of mouth and carcinoma of stomach. Apollon may relate with genesis and prognosis of tumor . It also may lead to drug resistance of certain tumors.
