Enteral versus parenteral nutrition support in patients with severe acute pancreatitis
10.3760/cma.j.issn.1673-4203.2009.11.004
- VernacularTitle:肠内外营养支持治疗重症急性胰腺炎的临床对比分析
- Author:
Chaoli HU
;
Xinguang QIU
;
Hongyi JIN
;
Hanhua DONG
- Publication Type:Journal Article
- Keywords:
pancreatitis;
enteral nutrition;
total parenteral nutrition
- From:
International Journal of Surgery
2009;36(11):729-733
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare enteral nutrition (EN) and total parenteral nutrition (TPN) in the treatment of severe acute pancreatitis(SAP) elucidate the advantage of EN. Methods Fifty-nine patients were assigned to TPN and EN groups. The nutritional index was detected, and the therapeutic efficacy was reviewed comparetively. Results After giving the nutritional support, the serum contents of albumin, pre-albumin, transferrin and beamoglobin were increased obviously (P < 0.05);and prealbumin, transferrin had statistical difference between the TPN and EN groups(P <0.05). APACHE Ⅱ score was lowered significant-ly in the EN group, comparing with the TPN group (P <0.05). In the EN group, complications, infection rate, food intake time, and hospitalization costs were significantly lower compared with the TPN group(P< 0.05), although mortality rate, hospital stay days had no statistical significance (P > 0.05). Conclusion EN is on ideal modality of nutrition support in SAP patients, which has many advantages in improving nu-tritional status, preserving gut mucosa barrier, decreasing bacterium and toxin shifting, regulating inflamma-tory and infective response, decreasing costs in the hospital.
