Living donor kidney transplantation in child: a report of 14 cases
10.3760/cma.j.issn.1673-4203.2009.11.007
- VernacularTitle:儿童亲属肾脏移植的临床研究
- Author:
Wei SUN
;
Lei ZHANG
;
Ye TIAN
- Publication Type:Journal Article
- Keywords:
renal transplantation;
child;
immunosuppressant
- From:
International Journal of Surgery
2009;36(11):739-741
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the benefits of living donor kidney transplantation in child, and to inves-tigate the procedures of renal transplantation, post-operative immunosuppressants regimens and complication management in child. Methods Clinical data, the prognosis of renal transplantation, operative procedure and immunosuppressive agents administrated in 14 children with end-stage renal disease (ESRD) undergo-ing renal transplantation were analyzed. Results The major complications in the early stage after renal transplantation were: 2 cases had acute rejection, 3 cases had severe hypernatremia, 1 case had urological infection, 3 cases had lymphocele. The major complications in the long-term recipients included: 6 cases had hypertension, 3 cases had hyperlipidemia, 4 cases had various kinds of infections, 5 cases had drug-in-duced hepatic injury. The one year survival rates of recipient/graft were all 100%. The average creatinine was 96.43 mmol/L(43-125 mmol/L) for the 14 recipients by the end of this study. All recipients thought their life quality was improved significantly. Conclusions Living donor kidney transplantation is the most ideal method to treat children with ESRD. Adult donor kidneys are suitable to the school age of recipients. The protocol of immunosuppressive therapy (prednisone plus MMF and FKS06) should be applied.
