Clinical manifestation and MRI feature on three patients of toxic encephalopathy after inhaling caffeine and sodium benzoate
10.3760/cma.j.issn.1006-7876.2009.11.012
- VernacularTitle:安钠咖相关脑损害三例临床与磁共振成像特点
- Author:
Yuping XING
;
Lifang ZHANG
;
Yufen WANG
;
Wanli SUN
;
Guihua WU
;
Yawei SHEN
;
Lixia CUI
- Publication Type:Journal Article
- Keywords:
Caffeine;
Sodium benzoate;
Poisoning;
Brain damage,chronic;
Magnetic resonance imaging
- From:
Chinese Journal of Neurology
2009;42(11):754-757
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical manifestation and MRI feature of toxic encephalopathy after inhaling caffeine and sodium benzoate. Methods Three patients with toxic encephalopathy induced by inhaling caffeine and sodium benzoate were observed clinically and with MRI. Results The 3 patients were male. They all had definite addiction histories (the time of addiction for 3 years to 7 years ). There were special language and retropulsive dystonia besides the common characteristics of toxic encephalopathy:reaction retardation and disturbance of intelligence. MRI showed the change of generalized demyelination in bilateral symmetrical cerebral hemisphere, posterior limbs of internal capsule, corpus callosum, medial lemniscus, and cerebellum hemisphere dentate nucleus. The clinical symptoms of 3 patients were significantly improved 40 days after the adrenocortical steroid and neurotrophic treatment. The mild mood disorder remained in case 1. Conclusion Clinical manifestation and MRI of toxic encephalopathy after inhaling caffeine and sodium benzoate are known, so we could diagnose the patients of the disease in time.
