Dermatological Applications of Iontophoresis.
- Author:
Seung Ho LEE
1
;
Chun Pill CHOI
;
Jiehoon KIM
Author Information
1. Department of Dermatology, Dongguk University Ilsan Hospital, College of Medicine, Dongguk University, Goyang, Korea. sholee@duih.org
- Publication Type:Review
- Keywords:
Drug delivery;
Iontophoresis
- MeSH:
Fees and Charges;
Iontophoresis;
Skin;
Skin Absorption
- From:Korean Journal of Dermatology
2013;51(6):409-414
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Transdermal drug delivery is applicable to only a few drugs because the stratum corneum is an excellent barrier to percutaneous absorption. Iontophoresis is a non-invasive technique which increases the drug deliveries into the skin through an electric current. In iontophoretic systems, the movement of ionized drugs is facilitated by electrical energy according to the basic electrical principles of "like charges repel each other and opposite charges attract". Iontophoresis has been explored for many dermatological applications with considerably successful reports. This article reviews the principles and advantages/limitations of iontophoresis, the factors affecting iontophoresis and its applications in various dermatological conditions.
